Seth Kahan on Grand Challenges

Sign up to receive the Seth Kahan’s weekly video enewsletter to be on the cutting edge of Grand Challenge news and initiatives! Subscribe safely and you can opt-out at any time.

May 8, 2025

Big, sweeping changes can happen, but they’re rare. History shows that even the toughest problems can be solved against the odds; those few successes stand out because most attempts fall short. When they succeed, they are like a mighty tree, drawing on diverse roots to erupt into multi-colored foliage that serves diverse constituents. Organizations and […]

Dr. Robert Jeraj on Medical Physics and its Role in Modern Healthcare

April 29, 2025

Medical physics plays a vital role in nearly every aspect of modern healthcare. From diagnostic scans, like CT imaging, to advanced treatments such as radiotherapy, medical physics is behind the technology and precision that drive these procedures. This video explores how medical physicists ensure the correct dose reaches the right patient, whether through imaging, therapy, […]

How to Deal with 2025 Disruptions

April 15, 2025

In today’s unpredictable environment, leadership demands energy, intention, clarity, and adaptability. This Disruption Playbook offers a roadmap for executives to lead with foresight and integrity amid political volatility, cultural shifts, and systemic uncertainty.

A Grand Challenge with the American Association of Physicists in Medicine and Dr. Ehsan Samei

March 18, 2025

Grand Challenge with the AAPM—focused on identifying bold, breakthrough challenges that could shape the future of medical physics.

My Grand Challenge Methodology: Conclusion

October 15, 2024

If I’ve learned anything in my work on Grand Challenges, it is how difficult it can be to take on systemic issues. Alone, it would be impossible. We need each other.

Ecosystems Activation

Tackle Wicked Problems with Ecosystem Activation

July 31, 2024

Wicked problems persist because multiple forces across the different dimensions of society perpetuate them. To solve a wicked problem, a Grand Challenge must summon forces that can bring about a better outcome. It must activate a beneficial ecosystem.

SST-Touchstone-Events

Getting Touchstone Events Right Matters: Here’s Why

July 16, 2024

Grand Challenges are driven forward by events, large and small. Every meeting provides a surge energized by those bond towards a common goal.

Grand Challenges: Background, Impact, and Implications

Grand Challenges: Background, Impact, and Implications

July 12, 2024

On every side, wicked problems demand a response–but what? How? Grand Challenges hold an answer. Do you hear it?

The First Annual Stop Stigma Together Summit is Coming to Salt Lake City This Summer

May 29, 2024

Stop Stigma Together is a crucial Touchstone Event to end the stigma against mental illness and substance use disorder.

The First National Summit to End Stigma: You’re Invited!

May 9, 2024

Learn how this Grand Challenge is scaling exponentially for maximum national impact to reduce mental health stigma together.

Implement-the-Plan

Creating a Social Movement? Implement the Plan

April 24, 2024

Implementing the Plan is incredibly exciting because it’s where the rubber meets the road. It creates the impact of a Grand Challenge.

Design-Summit

A Grand Challenge Design Summit Unites Participants, Catalyzes Thrust

April 1, 2024

A Design Summit has insularity. The intent is to create a time away from day-to-day life where a new movement can be launched.

Why Is the Health of Nurses So Important?

Healthy Nurse, Healthy Nation Challenge Five Years In

March 8, 2024

America’s 4 million registered nurses are suffering. Their health is worse than the average American in every dimension except smoking.

Want to Drive Change? Recognize Interdependencies

February 15, 2024

Wicked problems are complex system problems that demand interventions and the Grand Challenge methodology is a means of developing them.

Grand Challenge Archives

Scroll to Top